Catalina Garcia

Catalina Garcia added article Health
2025-02-21 06:13:18 -

Ribosomes: Orchestrators of Cellular Harmony and Enigmas in Disease
Cells, the microscopic building blocks of the human body, operate like a sophisticated symphony orchestra, finely orchestrating numerous life processes. In this diminutive yet intricate world, ribosomes function as conductors, guiding the synthesis of proteins—the essential constituents of life. However, disruptions in ribosomal function are frequently linked to cellular dysfunction,...

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Catalina Garcia added article Health
2025-02-21 03:59:10 -

The Immune Checkpoint Holds Great Promise for Cancer Immunotherapy
Cancer is a severe public health issue and one of the main causes of morbidity and mortality worldwide. However, the effect of chemoradiotherapy for cancer or tumor may be limited due to serious side effects and drug resistance. Therefore, it is essential to develop novel therapies for cancer treatment. In 2018, James P. Allison and Tasuku Honjo's research on the immune...

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Catalina Garcia added article Health
2025-01-21 06:57:29 -

Advancements in Non-IgG Antibody Discovery and Development: Transforming the Future of Therapy
In the fields of biotechnology and immunotherapy, antibodies have long been hailed as potent tools for treating various diseases, particularly cancer and autoimmune disorders. Traditionally, immunoglobulin G (IgG) antibodies have held a prominent position in this arena. However, recent breakthroughs in non-IgG antibody engineering have ushered in a new era of antibody engineering, paving...

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Catalina Garcia added article Health
2025-01-21 06:54:36 -

ADCC/CDC Enhancement in Therapeutic Antibody Development
Therapeutic antibodies, engineered through biotechnology, represent a specialized class of antibodies used in disease treatment. These antibodies are designed to target specific disease markers, such as malignant tumors, autoimmune disorders, and infectious diseases. Compared to traditional antibody therapies, therapeutic antibodies offer higher specificity and fewer side effects. In the...

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Catalina Garcia added article Health
2024-12-20 08:13:42 -

Enhancing Drug Development With Half-life Extension Strategies
The field of biopharmaceuticals is playing an increasingly pivotal role in medical treatment but is encountering several challenges. One pressing issue is the short half-life of many biopharmaceutical products, which leads to rapid degradation and clearance from the patient's body, necessitating frequent dosing. In this article, we explore how half-life extension strategies in drug development...

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Catalina Garcia added article Health
2024-12-20 08:11:44 -

Novel Therapies Based on Small-Molecule Antibodies Hold Immense Promise
Antibodies, the extraordinary proteins that serve as the frontline troops of the human immune system, have recently gained attention for their ability to combat tiny compounds known as haptens. Because of their small size, these elusive targets present particular difficulty for the immune system to identify as foreign invaders. However, researchers' inventiveness has resulted in the creation of...

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Catalina Garcia added article Health
2024-11-14 06:25:45 -

Scarless Wound Healing Achieved Through Stem Cell-Derived Exosomes
The journey of the human body begins in infancy, often marked by flawless perfection. However, as time elapses and individuals grow, the passage of time become evident on their skin. From minor mosquito bites to major surgical incisions or burns, wounds of varying sizes leave enduring marks on the body. While some wounds heal swiftly, leaving no visible trace, others persist over the years,...

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Catalina Garcia added article Health
2024-11-14 06:21:40 -

Liposome Drugs Show Potential Therapy Effectiveness
A novel liposome product, doxorubicin hydrocholoride liposomal injection, has received FDA approval as well as European Commission authorization to be used in the treatment of a variety of cancers, including ovarian cancer, acquired immune deficiency syndrome (AIDS)-related Kaposi's sarcoma, and multiple myeloma. It is no doubt another piece of good news for patients as well as researchers...

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Catalina Garcia added article Health
2024-10-11 08:15:45 -

Promising Strategies for Live Biotherapeutic Products Targeting Obesity
Obesity is spreading around the world and may contribute to a wide range of harmful conditions, such as cancer, diabetes, fatty liver, and cardiovascular disorders. Obesity can be caused by a variety of factors, such as a bad diet, insufficient rest or exercise, and heredity. Although altering one's lifestyle is still the most effective way to lose weight and improve metabolic symptoms, the use...

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Catalina Garcia added article Health
2024-10-11 08:12:47 -

Combination of intramuscular and intranasal mRNA vaccination induces more lung-resident memory T cells
In response to COVID-19 outbreaks, mRNA vaccine technology has been rapidly developed and successfully applied. the standard method of immunization with the SARS-CoV-2 mRNA vaccine consists of two intramuscular injections of immunization at 21 or 28 days intervals, followed by a booster immunization several months later. Advantages of mRNA vaccines include: * Strong immunogenicity against CD8+...

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