Article Review: Optimized Cholesterol-siRNA Chemistry Improves...

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2025-01-17 07:53:11 -

Article Review: Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles

As gene therapy and RNA-based treatments advance, small interfering RNA (siRNA) has emerged as a powerful tool for selectively targeting and silencing specific genes, offering significant potential for treating genetic disorders. However, the effective delivery of siRNA remains a major hurdle in translating these therapies into clinical practice. Extracellular vesicles, which are naturally...

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