MACS is a highly specific and rapid cell sorting technology based on magnetic particles that is widely used in immunology, stem cell research, oncology and clinical medicine. It employs antibody-conjugated magnetic particles to capture antigens on the surfaces of target cells, causing them to adhere to the sidewalls of a magnetic field. This separates unlabelled cells without bound magnetic particles from the cell suspension.

To meet the growing needs of scientists, CD Bioparticles now offers customized antibody-conjugated magnetic nanoparticles and cell sorting validation services. The diameter of the magnetic nanoparticles and the antibody conjugation method can both be tailored to specific requirements. For cell sorting validation, CD Bioparticles can provide relevant data on key parameters such as purity, viability and recovery rate.

The magnetic particles supplied by CD Bioparticles are engineered for optimal performance, ensuring minimal disruption to cells. They offer significant advantages in various biological fields, primarily due to their superior handling and performance characteristics. Their nanoscale size and dextran coating ensure excellent biocompatibility and minimal impact on cell function and viability, while also contributing to low non-specific binding. 

These particles are designed for simple and efficient separation, eliminating the need for expensive specialist equipment. Furthermore, they are easy to conjugate and, as they are suitable for high-temperature sterilisation prior to conjugation, they are better suited to aseptic control. This combination of features results in high cell purity and recovery. Their broad utility makes them ideal for a range of applications, including stem cell and cancer research, immunology, diagnostics, clinical applications, drug development and quality control in cell manufacturing.

CD Bioparticles' custom services provide researchers with critical flexibility. The company specializes in the synthesis of basic magnetic nanoparticles in a range of diameters, including 50 nm and greater than 200 nm, to perfectly match clients' experimental needs. For the 50 nm particles, separation requires a dedicated sorting column and matching magnetic frame, whereas particles with a diameter greater than 200 nm can be separated using an ordinary magnet without a sorting column. 

Additionally, CD Bioparticles provides antibody conjugation upon request, enabling researchers to select the desired coupling method, including chemical and biological conjugation based on streptavidin (SA)-biotin. CD Bioparticles also offers SA magnetic nanoparticles and biotinylated antibodies individually for flexible ratio adjustment. Furthermore, clients can request cell-sorting validation, for which CD Bioparticles can provide comprehensive data on the positive rate, viability and recovery for both the flow-through and retained fractions.

To know more information about the new services, or to contact the CD Bioparticles team for a consultation, quote, or proposal, please visit https://www.cd-bioparticles.com/s/Beads-Based-Cell-Isolation_28.html.

About CD Bioparticles

CD Bioparticles is a leading manufacturer and supplier of various nanoparticles, microparticles, and coatings for R&D as well as commercialization across different application areas, including in vitro diagnostics, biochemistry, cellular analysis, cell separation, and immunoassay. The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client specifications.